Chinese Journal of Tissue Engineering Research ›› 2013, Vol. 17 ›› Issue (48): 8349-8354.doi: 10.3969/j.issn.2095-4344.2013.48.009

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Topping-off technique for the protection of degenerative intervertebral disc

Zhao Cheng, Xu Jian-guang, Lian Xiao-feng, Li Hao, Qiu Man-le   

  1. Department of Orthopedics, the 6th Hospital Affiliated to Shanghai Jiao Tong University, Shanghai  200233, China
  • Online:2013-11-26 Published:2013-11-26
  • Contact: Xu Jian-guang, Department of Orthopedics, the 6th Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China jianguangxu2004@yahoo. com.cn
  • About author:Zhao Cheng★, Studying for master’s degree, Department of Orthopedics, the 6th Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China swilsonz@163.com
  • Supported by:

    Key Project of Science and Technology Committee of Shanghai for Medicine, No. 09411953500*

Abstract:

BACKGROUND: Topping-off technique can be used for fixation treatment through the combination of fusion and interspinous dynamic device, in order to prevent or slow down the adjacent lumbar segment degeneration. 
OBJECTIVE: To obverse the protective effect of Topping-off technique (posterior lumbar interbody fusion procedure combined with the fixation of dynamic interspinous device Coflex) for the degenerative intervertebral disc.
METHODS: A total of 32 patients with degenerative lumbar diseases who had been treated with Topping-off technique were included in this study. The Oswestry disability index, the Japanese Orthopaedic Association scores, range of motion for Coflex implanted segment and during the relative signal intensity of the Coflex implanted segment in MRI image were recorded and calculated preoperatively and the entire follow-up period.
RESULTS AND CONCLUSION: All patients were followed-up for 20.6 months averagely. Up to the last follow-up, the Oswestry disability index and Japanese Orthopaedic Association scores were significantly improved when compared with those before treatment (P < 0.001). There was no significant difference in the range of motion for Coflex implanted segment before and after treatment (P=0.19). The relative signal intensity of the Coflex implanted segment was significantly improved when compared with that before treatment (P < 0.01). The clinical application of the Topping-off technique showed a protective effect on the intervertebral disc.

Key words: lumbar vertebrae, intervertebral disk degeneration, spinal fusion, internal fixators

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